{"id":41065,"date":"2021-07-30T10:00:40","date_gmt":"2021-07-30T10:00:40","guid":{"rendered":"https:\/\/pr.asianetpakistan.com\/?p=77028"},"modified":"2021-07-30T10:00:40","modified_gmt":"2021-07-30T10:00:40","slug":"takeda-and-frazier-healthcare-partners-announce-collaboration-to-launch-hillevax-inc-to-develop-clinical-stage-norovirus-vaccine-candidate","status":"publish","type":"post","link":"https:\/\/dailysouthafrica.com\/takeda-and-frazier-healthcare-partners-announce-collaboration-to-launch-hillevax-inc-to-develop-clinical-stage-norovirus-vaccine-candidate\/","title":{"rendered":"Takeda and Frazier Healthcare Partners Announce Collaboration to Launch HilleVax, Inc. to Develop Clinical Stage Norovirus Vaccine Candidate"},"content":{"rendered":"
\n
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Takeda Will Focus its Efforts on Dengue, Zika and Pandemic Vaccines<\/h4>\n

Dubai, United Arab Emirates, July 30, 2021 (GLOBE NEWSWIRE) — Takeda Pharmaceutical Company Limited (TSE:4502\/NYSE:TAK<\/a>) (Takeda) and Frazier Healthcare Partners (Frazier) today announced a collaboration to launch HilleVax, Inc. (HilleVax), a biopharmaceutical company to develop and commercialize Takeda\u2019s norovirus vaccine candidate. Takeda has granted a license to HilleVax for the exclusive development and commercialization rights to its norovirus vaccine candidate, HIL-214 (formerly TAK-214), worldwide outside of Japan. Takeda will retain commercialization rights in Japan and HilleVax will integrate certain Japan development activities into its global development. Takeda remains committed to vaccines and this collaboration allows Takeda to focus primarily on dengue, COVID-19, pandemic influenza and Zika.<\/p>\n

HIL-214, which is a virus-like particle (VLP) based vaccine candidate, completed a randomized, placebo-controlled Phase 2b field efficacy study in 4,712 adult subjects in which HIL-214 was well-tolerated and demonstrated clinical proof of concept in preventing moderate-to-severe cases of acute gastroenteritis from norovirus infection.1<\/sup> To date, the candidate has been studied in nine human clinical trials with safety data from over 4,500 subjects and immunogenicity data from over 2,000 subjects.<\/p>\n

Ursula Belinda Myles, General Manager of Takeda\u2019s Access Market Cluster (covering much of Africa) commented: “Africa’s underlying burden of endemic diseases is one of the largest in the world, and infectious diseases play a larger portion of these diseases across the continent.\u00a0Like many other nations, COVID-19 has emphasized Africa’s greatest challenges around healthcare and highlighted the need for continued greater investment in healthcare systems. These investments are critical to secure economic development as Africa implements flagship projects around the 2030 Africa Health Strategy.”<\/p>\n

Ursula added: “The announcement of our partnership with Frazier Healthcare Partners will allow Takeda to focus efforts and resources on vaccines for diseases prevalent across Africa and provide support in alleviating the growing burden that infectious diseases have on public health systems.”<\/p>\n

Norovirus is a common intestinal infection marked by diarrhea, vomiting, abdominal cramps, nausea and sometimes fever that may lead to clinically significant dehydration.2<\/sup> Norovirus is recognized as the leading cause of acute gastroenteritis across the age spectrum.3<\/sup>\u00a0It is estimated that norovirus causes nearly 700 million cases of illness and more than 200,000 deaths worldwide per year\u00a0with significant additional economic and social burden.3<\/sup> No vaccines are currently approved for norovirus infection, and HIL-214 continues to be the most advanced norovirus vaccine candidate in human clinical trials.<\/p>\n

\u201cTakeda and Frazier have a history of successfully partnering together, and we are confident in HilleVax\u2019s capabilities to progress HIL-214, the most advanced norovirus vaccine candidate in development with the potential to address the huge global burden of norovirus-associated acute gastroenteritis,\u201d said Rajeev Venkayya, M.D., President of the Global Vaccine Business Unit, Takeda. \u201cThis will allow Takeda to focus its efforts and resources on our dengue vaccine, which we have begun filing for licensure around the world, our pandemic programs, and our partnership with the US Government to develop a Zika vaccine<\/p>\n

\u00a0Takeda\u2019s Commitment to Vaccines<\/b><\/p>\n

Vaccines prevent 2 to 3 million deaths each year and have transformed global public health. For more than 70 years, Takeda has supplied vaccines to protect the health of people in Japan. Today, Takeda\u2019s global vaccine business is applying innovation to tackle some of the world\u2019s most challenging infectious diseases, such as dengue, COVID-19, pandemic influenza and Zika. Takeda\u2019s team brings an outstanding track record and a wealth of knowledge in vaccine development and manufacturing to advance a pipeline of vaccines to address some of the world\u2019s most pressing public health needs. For more information, visit\u00a0www.TakedaVaccines.com<\/a>.<\/p>\n

About Takeda Pharmaceutical Company Limited<\/b>
\nTakeda Pharmaceutical Company Limited (
TSE:4502\/NYSE:TAK<\/a>) is a global, values-based, R&D-driven biopharmaceutical leader headquartered in Japan, committed to discover and deliver life-transforming treatments, guided by our commitment to patients, our people and the planet. Takeda focuses its R&D efforts on four therapeutic areas: Oncology, Rare Genetic and Hematology, Neuroscience and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. We are focusing on developing highly innovative medicines that contribute to making a difference in people’s lives by advancing the frontier of new treatment options and leveraging our enhanced collaborative R&D engine and capabilities to create a robust, modality-diverse pipeline. Our employees are committed to improving quality of life for patients and to working with our partners in health care in approximately 80 countries and regions. For more information, visit\u00a0https:\/\/www.takeda.com<\/a>.<\/p>\n

About Frazier Healthcare Partners<\/b><\/p>\n

Founded in 1991, Frazier Healthcare Partners is a leading provider of growth and venture capital to healthcare companies. With nearly $4.8 billion total capital raised, Frazier has invested in over 200 companies, with investment types ranging from company creation and venture capital to buyouts of profitable lower-middle market companies. The firm\u2019s Growth Buyout team invests in healthcare and pharmaceutical services, medical products and related sectors. The Life Sciences team invests in therapeutics and related areas that are addressing unmet medical needs through innovation. Frazier has offices in Seattle, WA and Menlo Park, CA, and invests broadly across the US, Canada, and Europe. For more information about Frazier Healthcare Partners, visit the company’s website at http:\/\/www.frazierhealthcare.com<\/a>.<\/p>\n

About HilleVax <\/b><\/p>\n

HilleVax is a biopharmaceutical company focused on the development and commercialization of novel vaccine candidates.\u00a0 Its initial program, HIL-214, is a virus-like particle (VLP) based vaccine candidate in development for the prevention of moderate-to-severe acute gastroenteritis caused by norovirus infection. For more information about HilleVax, visit the company\u2019s website at http:\/\/www.HilleVax.com<\/a>.<\/p>\n

Takeda Pharmaceutical Company Limited Forward-Looking Statements<\/b><\/p>\n

This press release and any materials distributed in connection with this press release may contain forward-looking statements, beliefs or opinions regarding Takeda\u2019s future business, future position and results of operations, including estimates, forecasts, targets and plans for Takeda. Without limitation, forward-looking statements often include words such as \u201ctargets\u201d, \u201cplans\u201d, \u201cbelieves\u201d, \u201chopes\u201d, \u201ccontinues\u201d, \u201cexpects\u201d, \u201caims\u201d, \u201cintends\u201d, \u201censures\u201d, \u201cwill\u201d, \u201cmay\u201d, \u201cshould\u201d, \u201cwould\u201d, \u201ccould\u201d \u201canticipates\u201d, \u201cestimates\u201d, \u201cprojects\u201d or similar expressions or the negative thereof. These forward-looking statements are based on assumptions about many important factors, including the following, which could cause actual results to differ materially from those expressed or implied by the forward-looking statements: the economic circumstances surrounding Takeda\u2019s global business, including general economic conditions in Japan and the United States; competitive pressures and developments; changes to applicable laws and regulations; the success of or failure of product development programs; decisions of regulatory authorities and the timing thereof; fluctuations in interest and currency exchange rates; claims or concerns regarding the safety or efficacy of marketed products or product candidates; the impact of health crises, like the novel coronavirus pandemic, on Takeda and its customers and suppliers, including foreign governments in countries in which Takeda operates, or on other facets of its business; the timing and impact of post-merger integration efforts with acquired companies; the ability to divest assets that are not core to Takeda\u2019s operations and the timing of any such divestment(s); and other factors identified in Takeda\u2019s most recent Annual Report on Form 20-F and Takeda\u2019s other reports filed with the U.S. Securities and Exchange Commission, available on Takeda\u2019s website at:\u00a0https:\/\/www.takeda.com\/investors\/reports\/sec-filings\/<\/a>\u00a0or at\u00a0www.sec.gov<\/a>. Takeda does not undertake to update any of the forward-looking statements contained in this press release or any other forward-looking statements it may make, except as required by law or stock exchange rule. Past performance is not an indicator of future results and the results or statements of Takeda in this press release may not be indicative of, and are not an estimate, forecast, guarantee or projection of Takeda\u2019s future results.<\/p>\n

\u00a0CONTACTS:<\/b><\/p>\n\n\n\n\n\n\n
Takeda Media Contacts:<\/b><\/td>\n<\/td>\n<\/tr>\n
Japanese Media<\/b><\/p>\n

Ryoko Matsumoto<\/p>\n

ryoko.matsumoto@takeda.com<\/b><\/a><\/p>\n

+81 (0) 3-3278-3414<\/td>\n

edia Outside Japan<\/b><\/p>\n

Amy Atwood<\/p>\n

amy.atwood@takeda.com<\/a><\/b><\/p>\n

+1-774-571-3316<\/td>\n<\/tr>\n

For HilleVax, Inc.:<\/b><\/td>\nFor Frazier Healthcare Partners:<\/b><\/td>\n<\/tr>\n
David Socks<\/p>\n

info@hillevax.com<\/a><\/b><\/p>\n

+1-650-325-5156<\/td>\n

Liz Park<\/p>\n

liz.park@frazierhealthcare.com<\/b><\/a><\/p>\n

+1-650-319-1831<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

References<\/b><\/p>\n

1 <\/sup><\/b>Sherwood J, et al. Vaccine 2020; 38(41):6442-6449<\/p>\n

2 <\/sup>https:\/\/ww.cdc.gov\/norovirus\/index.html<\/a> [accessed 2021 April 27].<\/p>\n

3 <\/sup>Hall AJ, et al. Expert Rev Vaccines 2016;15(8):949-951\"\"<\/p>\n

Mohammed Al Nasseri\nTakeda Pharmaceuticals\n+971507694646\nMohammed.alnasseri@fleishman.com<\/a><\/pre>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Takeda Will Focus its Efforts on Dengue, Zika and Pandemic Vaccines Dubai, United Arab Emirates, July 30, 2021 (GLOBE NEWSWIRE) \u2014 Takeda Pharmaceutical Company Limited (TSE:4502\/NYSE:TAK) (Takeda) and Frazier Healthcare Partners (Frazier) today announced a collaboration to launch HilleVax, Inc. (HilleVax), a biopharmaceutical company to develop and commercialize Takeda\u2019s norovirus vaccine candidate. Takeda has granted [\u2026]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[50],"tags":[],"yoast_head":"\nTakeda and Frazier Healthcare Partners Announce Collaboration to Launch HilleVax, Inc. to Develop Clinical Stage Norovirus Vaccine Candidate - Daily South Africa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dailysouthafrica.com\/takeda-and-frazier-healthcare-partners-announce-collaboration-to-launch-hillevax-inc-to-develop-clinical-stage-norovirus-vaccine-candidate\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Takeda and Frazier Healthcare Partners Announce Collaboration to Launch HilleVax, Inc. to Develop Clinical Stage Norovirus Vaccine Candidate - Daily South Africa\" \/>\n<meta property=\"og:description\" content=\"Takeda Will Focus its Efforts on Dengue, Zika and Pandemic Vaccines Dubai, United Arab Emirates, July 30, 2021 (GLOBE NEWSWIRE) \u2014 Takeda Pharmaceutical Company Limited (TSE:4502\/NYSE:TAK) (Takeda) and Frazier Healthcare Partners (Frazier) today announced a collaboration to launch HilleVax, Inc. 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